ASH – 2023 – Oral Presentation 483 […]
Archives: Publications
CD33-Deleted Hematopoietic Cells (Trem-Cel) Are Protected from CD33xCD3 Bispecific Antibody Treatment and Produce Significantly Reduced Levels of Inflammatory Cytokines in Preclinical Studies
Multimodal Atlas of Paired Diagnosis and Relapse AML Samples Enables Novel Therapeutic Targeting of Surface Antigens
ASH – 2023 – Oral Presentation 164 […]
Trem-cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Shows Rapid Primary Engraftment with CD33-Negative Hematopoiesis in Patients with High-Risk AML and Avoids Hematopoietic Toxicity During Gemtuzumab Ozogamicin (GO) Post-Hematopoietic Cell Transplant (HCT) Maintenance
HSCT² – 2023 – Oral Presentation […]
Novel CLL-1-directed CAR-T cells Mediate Potent Antigen-specific Cytolytic Activity in Mouse Models of Acute Myeloid Leukemia
SITC – 2023 – Poster Presentation P260 […]
Clinical Holds for Cell and Gene Therapy Trials: Risks, Impact, and Lessons Learned
Molecular Therapy: Methods & Clinical Development – Review […]
Read More… from Clinical Holds for Cell and Gene Therapy Trials: Risks, Impact, and Lessons Learned
GUMM: A Purpose-Built Computational Workflow for Single Cell Genotyping of Gene Editing Experiments
ESGCT – 2023 – Poster Presentation P726 […]
Development of a Gene Edited Next-Generation Hematopoietic Cell Transplant to Enable Acute Myeloid Leukemia Treatment by Solving Off-Tumor Toxicity
Molecular Therapy: Methods & Clinical Development – Peer-Reviewed Manuscript […]
A Single Cell DNA Sequencing Resource and Computational Approach to Quantify CRISPR-Cas9 Gene Editing Allelism
Cold Spring Harbor Lab Meeting – 2023 – Poster Presentation P203 […]