Novel CD33/CLL-1-directed dual CAR-T cells mediate potent antigen-specific cytolytic activity in mouse models of Acute Myeloid Leukemia (AML) […]
Publication Type: Oral Presentation
CRISPR-Based Therapy Analytical Development Summit – Oral Presentation
Analyzing Guide RNA (gRNA) Impurity Discovery & Quantification […]
Read More… from CRISPR-Based Therapy Analytical Development Summit – Oral Presentation
ASH – ORAL PRESENTATION – 483
Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Shows Rapid Primary Engraftment with CD33-Negative Hematopoiesis in Patients with High-Risk Acute Myeloid Leukemia (AML) and Avoids Hematopoietic Toxicity during Gemtuzumab Ozogamicin (GO) Maintenance Post-Hematopoietic Cell Transplant (HCT) […]
ASH – 2023 – ORAL PRESENTATION 164
Multimodal Atlas of Paired Diagnosis and Relapse AML Samples Enables Novel Therapeutic Targeting of Surface Antigens […]
HSCT² – 2023 – ORAL PRESENTATION
Trem-cel, a CRISPR/Cas9 gene-edited allograft lacking CD33, shows rapid primary engraftment with CD33-negative hematopoiesis in patients with high-risk AML and avoids hematopoietic toxicity during gemtuzumab ozogamicin (GO) post-hematopoietic cell transplant (HCT) maintenance […]
ESGCT – 2021 – Oral Presentation
VOR33: A Clinic-Ready CRISPR/Cas9 Engineered Hematopoietic Stem Cell Transplant for the Treatment of Acute Myeloid Leukemia […]
ASGCT – 2021 – Oral Presentation
VOR33: A Clinic-Ready CRISPR/Cas9 Engineered Hematopoietic Stem Cell Transplant for the Treatment of Acute Myeloid Leukemia […]