Gene-Edited Hematopoietic Stem Cells to Enable Next-Generation CAR-T Cell Therapy for the Treatment of AML […]
Publication Type: Poster Presentation
KEYSTONE SYMPOSIA – 2024 – POSTER PRESENTATION 1040
Uncovering Molecular and Functional Dynamics of Human Hematopoietic Stem Cells during In Vitro Culture for Cell Therapy Manufacturing […]
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Tandem Meetings – 2024 – Encore Poster Presentation 310
Trem-cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Shows Rapid Primary Engraftment with CD33-Negative Hematopoiesis in Patients with High-Risk Acute Myeloid Leukemia (AML) and Avoids Hematopoietic Toxicity During Gemtuzumab Ozogamicin (GO) Maintenance Post-Hematopoietic Cell Transplant (HCT) […]
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Tandem Meetings – 2024 – Encore Poster Presentation 293
Phase 1/2 Study of Donor-Derived Anti-CD33 Chimeric Antigen Receptor Expressing T Cells (VCAR33ALLO) in Patients with Relapsed or Refractory Acute Myeloid Leukemia After Allogeneic Hematopoietic Cell Transplantation (Trial in Progress) […]
Read More… from Tandem Meetings – 2024 – Encore Poster Presentation 293
Keystone Symposia – 2024 – Poster Presentation 2538
Leveraging CRISPR/Cas9 and HDR to create an engineered CD33 CAR-T to target AML […]
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ASH – 2023 – POSTER PRESENTATION – 4862
Phase 1/2 Study of Donor-Derived Anti-CD33 Chimeric Antigen Receptor Expressing T Cells (VCAR33) in Patients with Relapsed or Refractory Acute Myeloid Leukemia after Allogeneic Hematopoietic Cell Transplantation […]
ASH – 2023 – POSTER PRESENTATION 3425
CD33-Deleted Hematopoietic Cells (Trem-Cel) Are Protected from CD33xCD3 Bispecific Antibody Treatment and Produce Significantly Reduced Levels of Inflammatory Cytokines in Preclinical Studies […]
SITC – 2023 – POSTER PRESENTATION P260
Novel CLL-1-directed CAR-T cells Mediate Potent Antigen-specific Cytolytic Activity in Mouse Models of Acute Myeloid Leukemia […]
ESGCT – 2023 – Poster Presentation P726
GUMM: A Purpose-Built Computational Workflow for Single Cell Genotyping of Gene Editing Experiments […]